NIH-funded research R21 grant

Developing a soft robotic endoscope for early detection of colorectal cancer polyps

Official title: A Novel Framework for Sensitive and Reliable Early Diagnosis, Topographic Mapping, and Stiffness Classification of Colorectal Cancer Polyps

Funded at University of Texas at Austin · NIH-10891721 · Data updated 2026-11-12

This study is testing a new soft robotic tool that helps doctors find and understand colorectal cancer polyps better during exams, making it easier to spot issues early and improve treatment for patients.

More Colorectal Cancer research and trials

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniversity of Texas at Austin
NIH-funded
Lab location1 site (Austin, United States)
Project startJuly 20, 2023
Project endJune 30, 2026
Funding year2024
Award (this year)$211,275
NIH project number5R21CA280747-02
Project IDNIH-10891721 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals undergoing screening or evaluation for colorectal cancer, particularly those with polyps detected during colonoscopy.

Less likely to help

Patients who have already been diagnosed with advanced colorectal cancer or those without any gastrointestinal symptoms may not benefit from this research.

What this research studies

This research aims to create a soft robotic endoscope equipped with intelligent tactile sensing and advanced imaging technologies to improve the early detection and classification of colorectal cancer polyps. By utilizing machine learning and computer vision algorithms, the endoscope will provide real-time information about the size, shape, and stiffness of polyps during procedures. This innovative approach seeks to enhance the accuracy of diagnoses and treatment planning for gastrointestinal cancers, ultimately leading to better patient outcomes.

Why it matters

Potential benefit: If successful, this research could lead to earlier and more accurate diagnoses of colorectal cancer, improving treatment options and outcomes for patients.

How similar studies have gone: Previous research has shown promise in using robotic systems and machine learning for cancer detection, indicating that this approach could be a significant advancement in the field.

Where this research is happening

  • University of Texas at Austin
    Austin, United States
    Active

Researchers

  • Principal investigator: Alambeigi, Farshid — University of Texas at Austin
  • Study coordinator: Alambeigi, Farshid

Related research

Other NIH-funded projects on the same topics.

  • Improving colorectal cancer screening and follow-up care.

    This study is working to help more people get screened for colorectal cancer and receive the follow-up care they need, especially those who haven't been screened much before, so that everyone can have better access to important health checks and improve their overall health.

    NIH research Research Triangle Institute · Research Triangle Park, United States · NIH-9627071

  • Colorectal cancer prognosis through a broad, collaborative study

    A large, multi-center study follows people newly diagnosed with colorectal cancer to find biomarkers and patterns that predict outcomes and guide future care.

    NIH research Utah State Higher Education System--University of Utah · Salt Lake City, United States · NIH-11590756

  • Ceramides and how they affect metabolism and colorectal cancer in adults

    A study in adults with obesity-related health issues will explore how a fat-related molecule called ceramide influences metabolic problems and colorectal cancer risk.

    NIH research Utah State Higher Education System--University of Utah · Salt Lake City, United States · NIH-11535283

  • Automated point-of-care DNA methylation test for colorectal cancer in LMICs

    A fast, affordable blood test using DNA markers to help identify people at higher risk of colorectal cancer in low- and middle-income countries.

    NIH research Johns Hopkins University · Baltimore, United States · NIH-11531863

  • Rewiring Colorectal Cancer to Harness Therapeutic Hyperactivation

    A Yale team is exploring brain-storming new ways to treat colorectal cancer by safely boosting certain cancer signaling pathways to kill cancer cells and by reshaping cancer cell states to improve responses to existing therapies.

    NIH research Yale University · New Haven, United States · NIH-11505210

  • Comparative modeling to guide colorectal cancer screening and care

    A researcher team will use computer models to study how access to care, risk, and new screening options affect colorectal cancer outcomes and costs for adults in the US.

    NIH research Utah State Higher Education System--University of Utah · Salt Lake City, United States · NIH-11495363

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.