Developing a soft electronic device to treat resistant hypertension

3D Printed Soft and Stretchable Tissue-Like Bioadhesive Electronic Device Enabled Neuromodulation for Resistant Hypertension Therapy

NIH-funded research Pennsylvania State University, the · NIH-11158580

This study is testing a comfortable and flexible device that helps lower blood pressure for people with stubborn high blood pressure that doesn't respond to regular medications, making it easier for them to manage their condition.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionPennsylvania State University, the NIH-funded
Lab location1 site (University Park, United States)
Project IDNIH-11158580 on NIH RePORTER

What this research studies

This research aims to create a soft and stretchable bioadhesive electronic device designed to treat patients with resistant hypertension, a condition where blood pressure remains high despite medication. The device will utilize electrical activation of the carotid sinus baroreflex to help lower blood pressure effectively. Unlike existing devices, this new approach focuses on minimizing discomfort and tissue damage by being flexible and minimally invasive, allowing it to adapt to the body's movements. The goal is to provide a long-term solution for patients who do not respond to traditional hypertension treatments.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with resistant hypertension who have not achieved adequate blood pressure control with standard medications.

Not a fit: Patients with hypertension that responds well to medication may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide a new, effective treatment option for patients suffering from resistant hypertension.

How similar studies have performed: Previous research has shown promise in using neuromodulation techniques for hypertension, but this specific approach with a soft, stretchable device is novel.

Where this research is happening

University Park, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.