Developing a smart biorobot to help heal severe muscle injuries

An Intelligent Biorobot for the Regenerative Rehabilitation of Volumetric Muscle Loss Defects

['FUNDING_R01'] · CLEVELAND STATE UNIVERSITY · NIH-11043168

This study is testing a new biorobot that helps people with Volumetric Muscle Loss recover by using electrical stimulation and muscle cells, along with special rehab techniques, to improve muscle function and overall quality of life.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorCLEVELAND STATE UNIVERSITY (nih funded)
Locations1 site (CLEVELAND, UNITED STATES)
Trial IDNIH-11043168 on ClinicalTrials.gov

What this research studies

This research focuses on addressing Volumetric Muscle Loss (VML), a serious condition where significant muscle is lost due to trauma. The project aims to create an innovative biorobot that can deliver electrical stimulation and support muscle regeneration through the introduction of muscle cells. By combining this technology with specialized rehabilitation techniques, the goal is to enhance the recovery of muscle function and improve the quality of life for affected patients. Patients will be monitored to assess the effectiveness of this new approach in restoring muscle tissue and function.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals who have experienced significant muscle loss due to traumatic injuries.

Not a fit: Patients with muscle loss due to non-traumatic causes or those who are not candidates for surgical intervention may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved recovery and functionality for patients suffering from severe muscle injuries.

How similar studies have performed: While the approach of using intelligent biorobots for muscle regeneration is innovative, similar regenerative therapies have shown promise in preliminary studies.

Where this research is happening

CLEVELAND, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.