Developing a quick and affordable HPV test for cervical cancer screening in Mozambique
Sample-to-answer HPV DNA nucleic acid test for cervical cancer screening in Mozambique
This study is working on a simple and affordable test for HPV that can be used right in the doctor's office to help screen for cervical cancer in places like Mozambique, making it easier for more women to get the care they need.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rice University NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-10950476 on NIH RePORTER |
What this research studies
This research aims to create a point-of-care HPV DNA test that can be used for cervical cancer screening in low- and middle-income countries, particularly in Mozambique. The approach involves developing a novel, extraction-free, multiplexed nucleic acid amplification assay integrated with a lateral flow detection platform called NATFlow. This test is designed to be low-cost, rapid, and easy to use, addressing the barriers of traditional HPV testing methods that require extensive lab infrastructure and trained personnel. By improving access to effective screening, the project seeks to reduce cervical cancer incidence and mortality rates in underserved populations.
Who could benefit from this research
Good fit: Ideal candidates for this research are women in low- and middle-income countries, particularly those at risk for cervical cancer due to limited access to screening.
Not a fit: Patients living in high-income countries with established cervical cancer screening programs may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly enhance cervical cancer screening accessibility and early detection in low-resource settings.
How similar studies have performed: Other research has shown success in developing point-of-care tests for various conditions, indicating potential for this novel approach in cervical cancer screening.
Where this research is happening
Houston, United States
- Rice University — Houston, United States (Active)
Researchers
- Principal investigator: Richards-Kortum, Rebecca R. — Rice University
- Study coordinator: Richards-Kortum, Rebecca R.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.