Developing a platform to analyze RNA modifications
Engineered RNA Modification Recognition
['FUNDING_SBIR_2'] · ALIDA BIOSCIENCES, INC. · NIH-10920516
This study is working on a new tool that helps doctors and researchers better understand how tiny changes in RNA can affect health, especially in cancer, making it easier to use this information for diagnosis and treatment.
Quick facts
| Phase | ['FUNDING_SBIR_2'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | ALIDA BIOSCIENCES, INC. (nih funded) |
| Locations | 1 site (SAN DIEGO, UNITED STATES) |
| Trial ID | NIH-10920516 on ClinicalTrials.gov |
What this research studies
This research focuses on creating a commercial platform that analyzes the epitranscriptome, which includes all the natural chemical modifications to RNA that regulate its various biological functions. By integrating engineered RNA modification binding agents, the platform aims to enhance the sensitivity and selectivity of RNA analysis, particularly for clinical samples. The technology will provide a user-friendly workflow and cloud-based data handling, making it easier for researchers and clinicians to utilize RNA modifications as diagnostic tools and therapeutic targets, especially in cancer treatment.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients with cancers or conditions where RNA modifications play a significant role in disease progression or treatment response.
Not a fit: Patients with conditions unrelated to RNA biology or those who do not have access to the necessary diagnostic tools may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic and therapeutic strategies for cancer and other diseases by leveraging RNA modifications.
How similar studies have performed: Other research in the field of epitranscriptomics has shown promise, indicating that this approach could lead to significant advancements in understanding and treating diseases.
Where this research is happening
SAN DIEGO, UNITED STATES
- ALIDA BIOSCIENCES, INC. — SAN DIEGO, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MILES, ZACHARY — ALIDA BIOSCIENCES, INC.
- Study coordinator: MILES, ZACHARY
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.