Developing a platform for real-time monitoring of metabolites in biological systems
Official title: Sensor-Like LC-MS Platform for Rapid Online Monitoring of Metabolites in Biological Systems
Funded at Rowan University · NIH-10936154 · Data updated 2026-11-12
This study is working on a new, faster way to analyze tiny molecules in our bodies that can help us understand health better, using advanced technology to get quicker and more accurate results.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rowan University NIH-funded |
| Lab location | 1 site (Glassboro, United States) |
| Project start | September 15, 2024 |
| Project end | June 30, 2029 |
| Funding year | 2024 |
| Award (this year) | $375,000 |
| NIH project number | 1R35GM154693-01 |
| Project ID | NIH-10936154 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with conditions that involve metabolic changes, such as neurological disorders or those undergoing antibody therapy.
✕Less likely to help
Patients with stable metabolic conditions or those not undergoing treatment that affects metabolite levels may not benefit from this research.
What this research studies
This research focuses on creating an advanced liquid chromatography-mass spectrometry (LC-MS) platform that allows for rapid and real-time analysis of small molecule metabolites in biological systems. By utilizing innovative techniques such as microfluidic mixing and droplet-based injections, the platform aims to enhance the sensitivity and selectivity of metabolite detection. The project will also implement a unique derivatization device to improve the measurement process, allowing for quicker and more accurate results. This technology could significantly advance our understanding of complex biological processes and their implications for health.
Why it matters
Potential benefit: If successful, this research could lead to more precise monitoring of metabolites, improving diagnosis and treatment strategies for various health conditions.
How similar studies have gone: Previous research has shown promise in using advanced LC-MS techniques for metabolite analysis, indicating that this approach could yield significant advancements.
Where this research is happening
-
Rowan University
Glassboro, United States Active
Researchers
- Principal investigator: Grinias, James P — Rowan University
- Study coordinator: Grinias, James P
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.