Developing a platform for efficient drug discovery using virtual libraries
Efficient synthon-based modular screening of Giga-to-Terra-scale virtual libraries
['FUNDING_R01'] · UNIVERSITY OF SOUTHERN CALIFORNIA · NIH-10875654
This study is working on a new way to quickly find potential new medicines by using advanced computer techniques to test lots of different drug-like compounds, especially those that might work on cannabinoid receptors, which could help speed up the process of discovering new treatments for people.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF SOUTHERN CALIFORNIA (nih funded) |
| Locations | 1 site (Los Angeles, UNITED STATES) |
| Trial ID | NIH-10875654 on ClinicalTrials.gov |
What this research studies
This research aims to create a scalable platform that utilizes advanced computational techniques to screen vast libraries of drug-like compounds for potential new medications. By employing a novel approach called V-SYNTHES, the team will conduct structure-based virtual screenings on a massive scale, focusing on cannabinoid receptors and other protein targets. The methodology involves iteratively testing combinations of chemical structures to identify promising candidates while significantly reducing computational costs. This innovative approach could lead to faster and more efficient drug discovery processes.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions that may benefit from new cannabinoid-based therapies or other related treatments.
Not a fit: Patients who do not have conditions related to cannabinoid receptors or who are not seeking new drug therapies may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the discovery of new and effective drugs for various conditions, particularly those related to cannabinoid receptors.
How similar studies have performed: Other research has shown promise with similar virtual screening approaches, indicating a potential for success in this novel methodology.
Where this research is happening
Los Angeles, UNITED STATES
- UNIVERSITY OF SOUTHERN CALIFORNIA — Los Angeles, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: KATRITCH, VSEVOLOD — UNIVERSITY OF SOUTHERN CALIFORNIA
- Study coordinator: KATRITCH, VSEVOLOD
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.