Developing a non-invasive method to visualize cancerous tissues in real-time

OCT as a Platform for Non-Invasive Virtual H&E Biopsy

NIH-funded research Stanford University · NIH-10918088

This study is testing a new imaging technology that helps doctors see inside your body to check for cancer in brain tumors without needing to take any tissue samples, making it easier and more comfortable for patients.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionStanford University NIH-funded
Lab location1 site (Stanford, United States)
Project IDNIH-10918088 on NIH RePORTER

What this research studies

This research focuses on creating advanced imaging technology that allows doctors to perform virtual biopsies without needing to remove tissue samples. By using a technique called virtual H&E biopsy, the goal is to generate detailed images of living tissues, particularly for detecting cancerous cells in brain tumors. This method aims to provide real-time insights into tumor margins and invasiveness, which can help guide treatment decisions. The approach is designed to be non-invasive, potentially improving patient comfort and outcomes.

Who could benefit from this research

Good fit: Ideal candidates for this research include patients with brain tumors or other solid tumors who require accurate assessment of tumor margins.

Not a fit: Patients with non-solid tumors or those who do not require biopsy procedures may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more accurate and less invasive cancer diagnostics, improving treatment planning and patient outcomes.

How similar studies have performed: While the concept of virtual biopsies is innovative, similar imaging technologies have shown promise in other areas, indicating potential for success in this novel approach.

Where this research is happening

Stanford, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.