Developing a new x-ray system for advanced cancer treatment research
An ultra-high (FLASH) dose rate x-ray cabinet system for pre-clinical laboratory radiation research
This study is testing a new type of x-ray machine that delivers radiation quickly to help treat cancer while protecting healthy tissues, and it's designed for researchers who want to learn more about how this method can improve cancer care.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-10892966 on NIH RePORTER |
What this research studies
This research focuses on creating a novel x-ray cabinet system that can deliver high doses of radiation at ultra-high rates, known as FLASH radiotherapy. By using this innovative technology, researchers aim to better understand the biological effects of FLASH irradiation, which has shown promise in reducing damage to normal tissues while effectively targeting tumors. The project involves designing and constructing a self-shielded x-ray system that can facilitate preclinical studies, ultimately enhancing the capabilities of radiation research in laboratories. This approach combines advanced engineering with biological research to explore new avenues in cancer treatment.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with cancer who may benefit from innovative radiation therapies.
Not a fit: Patients who are not undergoing cancer treatment or those with conditions unrelated to radiation therapy may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to safer and more effective cancer treatments with fewer side effects for patients.
How similar studies have performed: Previous studies have shown promising results with FLASH radiotherapy, indicating potential for significant advancements in cancer treatment.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Rezaee, Mohammad — Johns Hopkins University
- Study coordinator: Rezaee, Mohammad
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.