Developing a new way to make influenza vaccines more effectively.
Integrated and Continuous Manufacturing of an Influenza Vaccine
This study is exploring a new way to make flu vaccines using cell technology instead of eggs, which could help create vaccines faster and make them work better, so people can get a more effective and affordable flu shot.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Michigan Technological University NIH-funded |
| Lab location | 1 site (Houghton, United States) |
| Project ID | NIH-11186865 on NIH RePORTER |
What this research studies
This research focuses on creating a new manufacturing process for influenza vaccines that uses cell-based technology instead of traditional egg-based methods. By continuously producing virus-like particles (VLPs), the team aims to make the vaccine production faster and more adaptable to changing virus strains. This approach could lead to a more effective vaccine that elicits a stronger immune response while also reducing production costs. Patients could benefit from a more effective and accessible influenza vaccine as a result of this innovative manufacturing process.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who are at risk of influenza infection, including those with chronic health conditions, the elderly, and healthcare workers.
Not a fit: Patients who are not at risk for influenza or those who have already received a vaccine may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and affordable influenza vaccines for patients.
How similar studies have performed: Other research has shown promise in developing cell-based vaccines, but this continuous manufacturing approach is relatively novel.
Where this research is happening
Houghton, United States
- Michigan Technological University — Houghton, United States (Active)
Researchers
- Principal investigator: Heldt, Caryn — Michigan Technological University
- Study coordinator: Heldt, Caryn
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.