Developing a new vaccine to prevent Q fever caused by Coxiella burnetii
Mimetic Peptides-Mediated Protection Against Coxiella burnetii Infection
This study is working on a new vaccine to help protect people from Q fever, using safe ingredients that won't cause serious side effects, so that everyone can have better protection against this illness.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas San Antonio NIH-funded |
| Lab location | 1 site (San Antonio, United States) |
| Project ID | NIH-10207396 on NIH RePORTER |
What this research studies
This research focuses on creating a safe and effective vaccine to protect against Q fever, a disease caused by the bacterium Coxiella burnetii. The current vaccine has serious side effects and is not commercially available in the U.S. The researchers are investigating a novel approach using mimetic peptides that mimic the bacterium's components to stimulate an immune response. By testing these peptides in combination with other proteins, they aim to develop a vaccine that provides strong protection without adverse effects.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults over 21 years old who are at risk of exposure to Coxiella burnetii.
Not a fit: Patients who are not at risk of exposure to Coxiella burnetii or those with existing immunity may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to a safe vaccine that prevents Q fever, improving public health and safety.
How similar studies have performed: Preliminary studies have shown promise with similar approaches, indicating potential for success in developing this vaccine.
Where this research is happening
San Antonio, United States
- University of Texas San Antonio — San Antonio, United States (Active)
Researchers
- Principal investigator: Zhang, Guoquan — University of Texas San Antonio
- Study coordinator: Zhang, Guoquan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.