Developing a new type of probe for advanced cellular imaging
Official title: A Biosinpired Genetically-Expressible Dual-Modality Peptide-Based Probe for Super-Resolution Correlative Light and Electron Microscopy
Funded at Photon Biosciences, LLC · NIH-10823128 · Data updated 2026-11-12
This study is working on a special tool that helps scientists see tiny parts of cells more clearly, which could improve how we understand diseases and develop better medical tests.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Photon Biosciences, LLC NIH-funded |
| Lab location | 1 site (Spokane, UNITED STATES) |
| Project start | January 1, 2024 |
| Project end | December 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $299,812 |
| NIH project number | 1R41GM153173-01 |
| Project ID | NIH-10823128 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with conditions that involve cellular abnormalities or diseases that could benefit from advanced imaging techniques.
✕Less likely to help
Patients with conditions that do not involve cellular imaging or those who are not undergoing treatment that requires such detailed analysis may not benefit from this research.
What this research studies
This research focuses on creating a genetically expressible probe that can be used in advanced imaging techniques to visualize cellular structures at an incredibly detailed level. By engineering a novel peptide-based probe, the project aims to combine the strengths of light and electron microscopy, allowing researchers to monitor single molecules within cells with high precision. This dual-modality approach will enhance our understanding of cellular processes and could lead to significant advancements in medical diagnostics.
Why it matters
Potential benefit: If successful, this research could provide a powerful new tool for diagnosing and understanding diseases at the cellular level.
How similar studies have gone: While there have been advancements in imaging techniques, the specific approach of using a genetically expressible dual-modality probe is relatively novel and has not been extensively tested.
Where this research is happening
-
Photon Biosciences, LLC
Spokane, United States Active
Researchers
- Principal investigator: Lewis, Kevin Michael — Photon Biosciences, LLC
- Study coordinator: Lewis, Kevin Michael
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.