Developing a new type of heart pump to reduce complications in heart failure patients
Flexible Anti-thrombotic LVADs
['FUNDING_R21'] · NORTH CAROLINA STATE UNIVERSITY RALEIGH · NIH-10706608
This study is testing a new heart pump designed to help people with severe heart failure by making it safer and more effective, so it can better support those waiting for a heart transplant or who can't get one.
Quick facts
| Phase | ['FUNDING_R21'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | NORTH CAROLINA STATE UNIVERSITY RALEIGH (nih funded) |
| Locations | 1 site (RALEIGH, UNITED STATES) |
| Trial ID | NIH-10706608 on ClinicalTrials.gov |
What this research studies
This research focuses on creating a new left ventricular assist device (LVAD) designed to help patients with severe heart failure. The innovative LVAD will feature flexible rotors and special coatings that aim to minimize blood damage and reduce the risk of dangerous blood clots. By optimizing these components, the research seeks to improve the safety and effectiveness of LVADs, which are critical for patients awaiting heart transplants or those who cannot receive one. The project involves extensive testing and characterization of the device's performance in laboratory settings.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients suffering from end-stage heart failure who may benefit from mechanical support like an LVAD.
Not a fit: Patients with mild heart failure or those who are not candidates for LVAD implantation may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to safer heart pumps that significantly improve the quality of life and outcomes for patients with heart failure.
How similar studies have performed: Previous research has shown promise in improving LVAD technology, but this specific approach with flexible rotors and anti-thrombotic coatings is relatively novel.
Where this research is happening
RALEIGH, UNITED STATES
- NORTH CAROLINA STATE UNIVERSITY RALEIGH — RALEIGH, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: KOTA, ARUN KUMAR — NORTH CAROLINA STATE UNIVERSITY RALEIGH
- Study coordinator: KOTA, ARUN KUMAR
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.