Developing a new type of flu vaccine adjuvant using yeast-based squalene.
Increasing Availability of Emulsion Adjuvants via Synthetic Biology
['FUNDING_OTHER'] · ENEPRET, INC. · NIH-10691630
This study is looking at a new way to make flu vaccines even better by using a natural ingredient from yeast, which could help protect you more effectively against the flu.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | ENEPRET, INC. (nih funded) |
| Locations | 1 site (LEXINGTON, UNITED STATES) |
| Trial ID | NIH-10691630 on ClinicalTrials.gov |
What this research studies
This research focuses on creating a new adjuvant for influenza vaccines by using sustainably sourced squalene from yeast cultures. The goal is to mimic the properties of an existing adjuvant, MF59, which enhances the effectiveness of vaccines. The research will involve preclinical testing to evaluate the safety and efficacy of this new adjuvant before moving towards large-scale production. Patients may benefit from improved flu vaccines that provide better protection against the virus.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who are at risk for influenza, including those with compromised immune systems or chronic health conditions.
Not a fit: Patients who are not at risk for influenza or those who have already received a flu vaccine may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective influenza vaccines that enhance immune responses.
How similar studies have performed: Previous research has shown that squalene-based emulsions can enhance vaccine efficacy, indicating a promising approach.
Where this research is happening
LEXINGTON, UNITED STATES
- ENEPRET, INC. — LEXINGTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: KEMPINSKI, CHASE — ENEPRET, INC.
- Study coordinator: KEMPINSKI, CHASE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.