Developing a new type of endomicroscope for brain imaging

Multi-probe minimally invasive endomicroscope

NIH-funded research Modendo INC. · NIH-10709909

This study is testing a new, tiny camera that can take detailed pictures of hard-to-reach parts of the brain without causing much harm, helping researchers learn more about how healthy and unhealthy brains work, which could improve how we diagnose and treat mental health issues.

Quick facts

Grant typeSbir 1 grant
Study typeNIH-funded research
Funding institutionModendo INC. NIH-funded
Lab location1 site (Boulder, United States)
Project IDNIH-10709909 on NIH RePORTER

What this research studies

This research focuses on creating a multi-probe ultrathin endomicroscope designed to provide high-resolution imaging and photo-stimulation in hard-to-reach areas of the brain. The device aims to be minimally invasive, allowing for the examination of brain regions like the brain stem and olfactory bulb with minimal damage to surrounding tissues. By using this innovative technology, researchers hope to gain insights into brain connectivity and differences between healthy and diseased brains, which could lead to advancements in diagnosing and treating mental health disorders.

Who could benefit from this research

Good fit: Ideal candidates for this research would be individuals suffering from mental health disorders who may benefit from advanced diagnostic techniques.

Not a fit: Patients with conditions that do not involve deep brain structures or those who are not candidates for invasive procedures may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved diagnostic tools and treatment options for patients with mental health disorders.

How similar studies have performed: While the approach of using multi-probe endomicroscopes is innovative, similar technologies in minimally invasive imaging have shown promise in other medical fields.

Where this research is happening

Boulder, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Mental disordersMental health disordersPsychiatric DiseasePsychiatric Disorder
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.