Developing a new treatment to prevent infections and gastrointestinal issues from chemotherapy
Preventing chemotherapy-related toxicities and infections with a novel phosphorylated triblock copolymer
This study is testing a new treatment designed to help protect your gut health during chemotherapy, making it safer and more effective by reducing the risk of infections and other problems.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Covira Surgical NIH-funded |
| Lab location | 1 site (North Chicago, United States) |
| Project ID | NIH-10821023 on NIH RePORTER |
What this research studies
This research focuses on creating a novel agent that aims to prevent gastrointestinal toxicities and infections that often occur in patients undergoing chemotherapy. Chemotherapy can disrupt the gut microbiome and lead to serious complications, including increased susceptibility to infections. The approach involves preserving the beneficial aspects of the gut microbiome while mitigating its harmful effects, thus improving patient outcomes. By addressing these issues, the research seeks to enhance the safety and effectiveness of chemotherapy treatments.
Who could benefit from this research
Good fit: Ideal candidates for this research are cancer patients who are undergoing chemotherapy and are at risk for gastrointestinal toxicities and infections.
Not a fit: Patients who are not undergoing chemotherapy or those with pre-existing gastrointestinal conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly reduce the risk of infections and gastrointestinal complications for chemotherapy patients.
How similar studies have performed: While the approach is innovative, there is a growing body of research exploring the preservation of gut microbiome health during chemotherapy, indicating potential for success.
Where this research is happening
North Chicago, United States
- Covira Surgical — North Chicago, United States (Active)
Researchers
- Principal investigator: Hennessey, Patrick — Covira Surgical
- Study coordinator: Hennessey, Patrick
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.