Developing a new treatment to prevent cholera outbreaks using bacteriophages.
Manufacturing and Formulation Process Development for a Prophylactic Cholera Phage Cocktail
['FUNDING_SBIR_2'] · PHAGEPRO, INC. · NIH-11068008
This study is testing a special mix of viruses that can help prevent cholera, a serious illness that causes severe diarrhea, especially for people who have been around someone who is infected.
Quick facts
| Phase | ['FUNDING_SBIR_2'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | PHAGEPRO, INC. (nih funded) |
| Locations | 1 site (Mansfield, UNITED STATES) |
| Trial ID | NIH-11068008 on ClinicalTrials.gov |
What this research studies
This research focuses on creating a prophylactic cholera phage cocktail to prevent the spread of cholera, a severe diarrheal disease caused by the bacterium Vibrio cholerae. The approach involves formulating a targeted treatment that can act quickly to reduce the risk of cholera transmission in communities, especially among those who have been in contact with infected individuals. By utilizing bacteriophages, which are viruses that specifically target bacteria, this research aims to provide a novel solution to combat cholera outbreaks effectively.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals living in areas with high cholera prevalence or those who have been in close contact with cholera patients.
Not a fit: Patients who are not at risk for cholera or those living in regions with low incidence of the disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly reduce cholera transmission and improve public health outcomes in at-risk communities.
How similar studies have performed: While the use of bacteriophages in treating bacterial infections has shown promise, this specific approach to cholera prevention is novel and has not been extensively tested.
Where this research is happening
Mansfield, UNITED STATES
- PHAGEPRO, INC. — Mansfield, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: YEN, MINMIN — PHAGEPRO, INC.
- Study coordinator: YEN, MINMIN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.