Developing a new treatment to improve bladder and bowel control for certain patients.
LIQUID CHROMATOGRAPHY WITH TANDEM MASS SPECTROMETRY (HPLC-MS-MS) ASSAY VALIDATION AND SAMPLE TESTING
This study is testing a new peptide drug that aims to help people with spinal injuries, multiple sclerosis, or diabetes regain better control over their bladder and bowel, which could make managing incontinence easier and improve their daily lives.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Battelle Centers/pub Hlth Res & Evaluatn NIH-funded |
| Lab location | 1 site (Columbus, United States) |
| Project ID | NIH-10949055 on NIH RePORTER |
What this research studies
This research focuses on creating a peptide drug that targets the neurokinin2 receptor to help restore bladder and bowel control in individuals suffering from spinal injuries, multiple sclerosis, or diabetes. The project aims to optimize a lead peptide called DTI-117 and assess its effectiveness through various pre-clinical studies and regulatory processes. Patients may benefit from this innovative approach as it could lead to improved management of incontinence and related symptoms. The research will involve both laboratory and clinical trial evaluations to ensure safety and efficacy.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with spinal injuries, multiple sclerosis, or diabetes who experience bladder and bowel control problems.
Not a fit: Patients without spinal injuries, multiple sclerosis, or diabetes are unlikely to benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly improve the quality of life for patients with bladder and bowel control issues.
How similar studies have performed: Other research has shown promise in developing receptor-targeted therapies for similar conditions, indicating potential success for this approach.
Where this research is happening
Columbus, United States
- Battelle Centers/pub Hlth Res & Evaluatn — Columbus, United States (Active)
Researchers
- Principal investigator: Burnaugh, Amanda — Battelle Centers/pub Hlth Res & Evaluatn
- Study coordinator: Burnaugh, Amanda
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.