Developing a new treatment for severe mouth sores in cancer patients

IND-enabling toxicology studies to reach IND approval for a proprietary biologic to treat oral mucositis in cancer patients

NIH-funded research Allander Biotechnologies, INC. · NIH-10933015

This study is testing a new gel treatment for mouth sores that can happen during cancer radiation therapy, aiming to help patients heal better and feel more comfortable while they receive their treatment.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionAllander Biotechnologies, INC. NIH-funded
Lab location1 site (Aurora, United States)
Project IDNIH-10933015 on NIH RePORTER

What this research studies

This research focuses on creating a new biologic treatment for oral mucositis, a painful condition that often affects cancer patients undergoing radiation therapy. The approach involves applying a specially formulated gel to the oral mucosa, which has shown promising results in preclinical trials with animals. The goal is to improve healing and reduce the severity of mouth sores, allowing patients to tolerate cancer treatments better. The research will also ensure that the treatment meets regulatory standards for safety and efficacy.

Who could benefit from this research

Good fit: Ideal candidates for this research are cancer patients undergoing radiation therapy who are at risk of developing oral mucositis.

Not a fit: Patients who are not undergoing radiation therapy or who do not develop oral mucositis may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide a new effective treatment option for cancer patients suffering from oral mucositis, improving their quality of life and treatment outcomes.

How similar studies have performed: Previous research has shown success with similar biologic treatments in animal models, indicating potential for effective application in humans.

Where this research is happening

Aurora, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.