Developing a new treatment for lung injury caused by radiation exposure

THE PHARMACOLOGICAL DEVELOPMENT OF IPW-5371 FUMARATE AS A RADIATION MEDICAL COUNTERMEASURE FOR THE TREATMENT OF DELAYED RADIATION LUNG INJURY UNDER THE FDA ANIMAL RULE

NIH-funded research Innovation Pathways, LLC · NIH-11111142

This study is looking at how a special drug called IPW-5371 Fumarate might help protect lung health after radiation exposure, using animal models to find out if it can reduce lung damage, with hopes that it could lead to new treatments for people in the future.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionInnovation Pathways, LLC NIH-funded
Lab location1 site (Palo Alto, United States)
Project IDNIH-11111142 on NIH RePORTER

What this research studies

This research investigates the effects of radiation exposure on lung health using animal models. It focuses on a specific drug, IPW-5371 Fumarate, which aims to mitigate the delayed effects of radiation-induced lung injury. The study follows FDA guidelines to ensure that the findings can support future human applications. By understanding how this drug interacts with the body after radiation exposure, the research hopes to pave the way for effective treatments.

Who could benefit from this research

Good fit: Ideal candidates for this research would be individuals who have experienced radiation exposure and are at risk of developing lung injuries.

Not a fit: Patients who have not been exposed to radiation or do not have lung injury concerns may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to a new treatment option for patients suffering from lung injuries caused by radiation exposure.

How similar studies have performed: While this approach is novel in the context of lung injury from radiation, similar pharmacological interventions have shown promise in other areas of radiation medicine.

Where this research is happening

Palo Alto, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.