NIH-funded research NIH-funded research

Developing a new treatment for gonorrhea

Official title: A broad spectrum anti-gonorrhea immunotherapeutic

Funded at Planet Biotechnology, INC. · NIH-11066542 · Data updated 2026-11-12

This study is exploring a new way to help your body fight gonorrhea, especially the tougher strains that don't respond to antibiotics, by using a special protein that boosts your immune system to target and kill the bacteria.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionPlanet Biotechnology, INC.
NIH-funded
Lab location1 site (Hayward, United States)
Project startApril 4, 2024
Project endMarch 31, 2026
Funding year2025
Award (this year)$296,920
NIH project number5R41AI179576-02
Project IDNIH-11066542 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals diagnosed with gonorrhea, particularly those who have not responded to standard antibiotic treatments.

Less likely to help

Patients who do not have gonorrhea or those with other unrelated health conditions may not benefit from this research.

What this research studies

This research focuses on creating a new immunotherapeutic approach to treat gonorrhea, a sexually transmitted infection that has seen a rise in antibiotic resistance. The team is investigating a chimeric protein that can effectively kill the bacteria responsible for gonorrhea by utilizing the body's immune system. Through laboratory studies, they aim to demonstrate the effectiveness of this treatment against various strains of the bacteria, particularly those that are resistant to current antibiotics.

Why it matters

Potential benefit: If successful, this research could provide a new, effective treatment option for gonorrhea, especially for patients with antibiotic-resistant infections.

How similar studies have gone: While the approach of using immunotherapeutics is promising, it is relatively novel in the context of gonorrhea treatment, and similar strategies have shown varying degrees of success in other infectious diseases.

Where this research is happening

  • Planet Biotechnology, INC.
    Hayward, United States
    Active

Researchers

  • Principal investigator: Wycoff, Keith — Planet Biotechnology, INC.
  • Study coordinator: Wycoff, Keith

Related research

Other NIH-funded projects on the same topics.

  • Topical two-target antibody to prevent gonorrhea

    A gel with a two-target antibody designed to block gonorrhea bacteria when applied to genital areas for people at risk.

    NIH research Planet Biotechnology, INC. · Hayward, United States · NIH-11146691

  • A New Shot to Prevent Tick-Borne Illnesses

    This project is creating a new yearly shot, called Fc3/SCR(19-20), to protect people from Lyme Disease and Relapsing Fever.

    NIH research Planet Biotechnology, INC. · Hayward, United States · NIH-11140476

  • A new way to prevent Rickettsia infections

    We are working on a new protective treatment to help prevent serious Rickettsia infections like Rocky Mountain spotted fever.

    NIH research Planet Biotechnology, INC. · Hayward, United States · NIH-11136342

  • Developing a new treatment to prevent severe infections from Rickettsia bacteria

    This study is testing a new treatment that aims to help protect people from serious infections caused by Rickettsia, which are spread by insect bites, by boosting the immune system's ability to fight off these bacteria.

    NIH research Planet Biotechnology, INC. · Hayward, United States · NIH-11013481

  • A new treatment to prevent gonorrhea using bispecific antibodies applied topically.

    This study is exploring a new way to help prevent gonorrhea using a special cream that boosts your body's defenses against the bacteria that cause the infection, offering a potentially safer and more effective option for those at risk.

    NIH research Planet Biotechnology, INC. · Hayward, United States · NIH-11013480

  • Creating a new treatment to prevent tick-borne diseases

    This study is testing a new protein treatment that could help prevent Lyme Disease and Relapsing Fever with just one injection a year, making it suitable for everyone, including those with weaker immune systems, and aims to make it safe and effective for the whole tick season.

    NIH research Planet Biotechnology, INC. · Hayward, United States · NIH-10925734

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.