Developing a new tool for measuring radiation doses in cancer treatment

3D In vivo dosimetry for FLASH proton therapy

NIH-funded research University of California-Irvine · NIH-10849547

This study is working on a new device that will help doctors measure radiation levels during a special cancer treatment called proton FLASH therapy, making sure tumors get the right dose while protecting healthy tissue, and it aims to be ready for use in hospitals in the next 5-10 years.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionUniversity of California-Irvine NIH-funded
Lab location1 site (Irvine, United States)
Project IDNIH-10849547 on NIH RePORTER

What this research studies

This research focuses on creating a new type of dosimeter that can accurately measure radiation doses during proton FLASH therapy, a cutting-edge cancer treatment that delivers high doses of radiation quickly. The project aims to ensure that the right amount of radiation is delivered to tumors while minimizing damage to surrounding healthy tissues. By forming a collaborative team of experts from various fields, the research seeks to bring this innovative dosimeter into clinical use within the next 5-10 years, addressing a critical need in cancer care.

Who could benefit from this research

Good fit: Ideal candidates for this research are cancer patients who are undergoing proton FLASH therapy.

Not a fit: Patients who are not receiving radiation therapy or those with conditions that do not involve proton FLASH therapy may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to safer and more effective cancer treatments by improving the precision of radiation delivery.

How similar studies have performed: While the approach of using protoacoustic imaging for dosimetry is innovative, similar research in radiation therapy has shown promise in improving treatment accuracy.

Where this research is happening

Irvine, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acute Radiation Syndrome
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.