Developing a new tool for examining tissue samples without dyes
Label-free digital cytopathology using deep-ultraviolet coded ptychography with intrinsic molecular contrast
['FUNDING_R01'] · UNIVERSITY OF CONNECTICUT STORRS · NIH-10870053
This study is testing a new digital tool that uses special light to look at tissue samples without needing dyes, which could help doctors get faster and more accurate results for diagnosing conditions.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CONNECTICUT STORRS (nih funded) |
| Locations | 1 site (STORRS-MANSFIELD, UNITED STATES) |
| Trial ID | NIH-10870053 on ClinicalTrials.gov |
What this research studies
This research focuses on creating a novel digital cytopathology tool that allows for the examination of tissue samples without the need for traditional dye staining. By utilizing deep-ultraviolet light, the tool can directly interact with the biomolecules in cells, providing detailed information about their structure and composition. This method aims to significantly reduce the time required for histopathological analysis, enabling quicker diagnosis and treatment decisions. The approach involves advanced imaging techniques that do not rely on conventional microscopy, making it a potentially transformative technology in medical diagnostics.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals requiring histopathological examination of tissue samples, such as those with suspected tumors or other cellular abnormalities.
Not a fit: Patients who do not require tissue analysis or those with conditions that do not involve cellular examination may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to faster and more accurate diagnoses for patients, improving treatment outcomes.
How similar studies have performed: While the approach of using deep-ultraviolet light for cytopathology is innovative, similar techniques in other imaging modalities have shown promise in enhancing diagnostic capabilities.
Where this research is happening
STORRS-MANSFIELD, UNITED STATES
- UNIVERSITY OF CONNECTICUT STORRS — STORRS-MANSFIELD, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ZHENG, GUOAN — UNIVERSITY OF CONNECTICUT STORRS
- Study coordinator: ZHENG, GUOAN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.