Developing a new tool for analyzing cancer cells to improve treatment selection
Official title: Rapid, Single Cell Proteomic Profiling for Biomarker Development in Precision Oncology
Funded at Aperture Bio, INC. · NIH-10911716 · Data updated 2026-11-12
This study is working on a new tool that looks closely at individual cancer cells to help doctors better understand which patients might benefit from the latest cancer treatments, making it easier for more clinics to use.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Aperture Bio, INC. NIH-funded |
| Lab location | 1 site (Allston, United States) |
| Project start | May 20, 2024 |
| Project end | November 30, 2025 |
| Funding year | 2024 |
| Award (this year) | $339,990 |
| NIH project number | 1R42CA290912-01 |
| Project ID | NIH-10911716 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are cancer patients who are undergoing treatment and may benefit from more precise diagnostic tools.
✕Less likely to help
Patients with cancers that are not amenable to the types of analysis being developed may not receive benefits from this research.
What this research studies
This research focuses on creating a novel diagnostic tool that can analyze cancer cells at a single-cell level, providing detailed information about protein expression and cell states. By utilizing advanced techniques that improve upon traditional methods, the project aims to enhance the accuracy of patient selection for next-generation cancer therapies. The goal is to develop a platform that can be used with standard laboratory equipment, making it accessible for broader clinical use. This approach seeks to address the significant challenges faced by oncologists in determining which patients are likely to benefit from specific treatments.
Why it matters
Potential benefit: If successful, this research could lead to more personalized and effective cancer treatments by enabling better patient selection for therapies.
How similar studies have gone: Other research has shown promise in developing advanced diagnostic tools for cancer, but this specific approach is relatively novel.
Where this research is happening
-
Aperture Bio, INC.
Allston, United States Active
Researchers
- Principal investigator: Peterson, Hannah Marie — Aperture Bio, INC.
- Study coordinator: Peterson, Hannah Marie
Related research
Other NIH-funded projects on the same topics.
-
Fast single-cell protein test to help guide cancer treatment
A company is developing a quick test that reads proteins in individual tumor and immune cells to help doctors pick better treatments for people with cancer.
-
Using advanced imaging to study live cancer cells
This study is looking at how special imaging tools can help us see live cancer cells in action, which could give us better ideas about how tumors react to different treatments, ultimately helping to tailor therapies for patients like you.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.