Developing a new technology to record electrical signals in cells.
Three-dimensional field effect transistor arrays as a platform technology for intracellular electrophysiology recording.
This study is working on a new, gentle device that can connect with your cells to pick up their electrical signals, which could help us better understand and treat conditions like Alzheimer's and epilepsy.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Diego NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project ID | NIH-10863861 on NIH RePORTER |
What this research studies
This research focuses on creating a soft electronic interface that can seamlessly integrate with cells and tissues to record their electrical signals. By using a three-dimensional field effect transistor array, the project aims to capture the ionic movements that are crucial for cell signaling, which can be disrupted in diseases like Alzheimer's and epilepsy. The innovative design allows for better signal quality and longer recording times compared to traditional methods. Patients may benefit from improved understanding and treatment of conditions related to cellular signaling dysfunction.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with neurological conditions such as Alzheimer's disease or epilepsy.
Not a fit: Patients with conditions unrelated to cellular signaling dysfunction may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better diagnostic tools and treatments for neurological diseases.
How similar studies have performed: Other research has shown promise in using advanced electronic interfaces for cellular studies, indicating potential for success in this novel approach.
Where this research is happening
La Jolla, United States
- University of California, San Diego — La Jolla, United States (Active)
Researchers
- Principal investigator: Xu, Sheng — University of California, San Diego
- Study coordinator: Xu, Sheng
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.