Developing a new sealant to make dental restorations last longer
Biofunctional sealant with peptides to extend lifespans of Class V restorations
['FUNDING_FELLOWSHIP'] · UNIVERSITY OF MINNESOTA · NIH-11331929
This study is looking at ways to make dental fillings in the lower part of your teeth last longer by creating a special sealant that helps keep bacteria out, so you can enjoy better dental health and fewer trips to the dentist for replacements.
Quick facts
| Phase | ['FUNDING_FELLOWSHIP'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF MINNESOTA (nih funded) |
| Locations | 1 site (MINNEAPOLIS, UNITED STATES) |
| Trial ID | NIH-11331929 on ClinicalTrials.gov |
What this research studies
This research focuses on improving the durability of Class V dental restorations, which are commonly used in the lower part of teeth and are prone to failure due to water and bacteria. The study aims to create a biofunctional sealant that enhances the bond between the restorative material and surrounding tissue, potentially preventing bacterial degradation. By exploring how oral cells interact with these materials, the research seeks to develop innovative solutions that could lead to longer-lasting dental restorations. Patients may benefit from improved dental health and fewer replacements of these restorations.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who require Class V dental restorations, particularly older adults who are more likely to need these procedures.
Not a fit: Patients who do not require dental restorations or have no history of dental issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to longer-lasting dental restorations, reducing the need for frequent dental procedures.
How similar studies have performed: While there has been some research on improving dental materials, this specific approach to enhancing Class V restorations with biofunctional sealants is relatively novel.
Where this research is happening
MINNEAPOLIS, UNITED STATES
- UNIVERSITY OF MINNESOTA — MINNEAPOLIS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: FISCHER, NICHOLAS G — UNIVERSITY OF MINNESOTA
- Study coordinator: FISCHER, NICHOLAS G
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.