Developing a new optical method to measure activity in the retina

Optoretinography: All-optical measures of functional activity in the human retina

['FUNDING_U01'] · UNIVERSITY OF WASHINGTON · NIH-10917168

This study is testing a new, gentle way to look at how well your retina is working by using light, which could help doctors see how effective treatments are for retinal diseases.

Quick facts

Phase['FUNDING_U01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF WASHINGTON (nih funded)
Locations1 site (SEATTLE, UNITED STATES)
Trial IDNIH-10917168 on ClinicalTrials.gov

What this research studies

This research focuses on creating a non-invasive optical technique called optoretinography (ORG) to monitor retinal function and assess the effectiveness of treatments for retinal diseases. By using advanced imaging methods, the researchers aim to visualize how retinal neurons respond to light, providing insights into their health and functionality. The ORG technique is designed to offer high sensitivity and resolution, allowing for detailed observation of neural activity at various scales and timeframes. This innovative approach could significantly enhance our understanding of retinal diseases and improve clinical assessments.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals with retinal diseases who require monitoring of their retinal function.

Not a fit: Patients with healthy retinas or those without retinal diseases may not receive any benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better monitoring and treatment options for patients with retinal diseases.

How similar studies have performed: Other research has shown promise in using optical techniques for assessing retinal function, making this approach both innovative and grounded in prior successes.

Where this research is happening

SEATTLE, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.