Developing a new mouse model for a rare type of uterine cancer
A novel uterine leiomyosarcoma mouse model for therapeutic development
This study is creating special mice that have a type of uterine cancer called leiomyosarcoma, so researchers can learn more about the disease and find better treatments for people who have it.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Tx Md Anderson Can Ctr NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-11010400 on NIH RePORTER |
What this research studies
This research focuses on creating a mouse model that mimics uterine leiomyosarcoma, a rare and aggressive cancer of the uterus. By genetically modifying mice to replicate specific mutations found in human cases, the researchers aim to better understand the disease and test new treatment strategies. This model will help bridge the gap between laboratory findings and clinical applications, ultimately supporting the development of effective therapies for patients. The study addresses the urgent need for preclinical models that can facilitate clinical trial readiness for this challenging cancer.
Who could benefit from this research
Good fit: Ideal candidates for this research are women diagnosed with uterine leiomyosarcoma or those at high risk for developing this rare cancer.
Not a fit: Patients with other types of uterine cancers or those without a diagnosis of uterine leiomyosarcoma may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatment options for women diagnosed with uterine leiomyosarcoma.
How similar studies have performed: While there have been studies on other cancer models, this specific approach to uterine leiomyosarcoma is relatively novel and untested.
Where this research is happening
Houston, United States
- University of Tx Md Anderson Can Ctr — Houston, United States (Active)
Researchers
- Principal investigator: Wong, Kwong Kwok — University of Tx Md Anderson Can Ctr
- Study coordinator: Wong, Kwong Kwok
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.