Developing a new microscope for detailed imaging of infectious diseases

Novel Optical Scanning Probe Microscope for Biomedical Chemical Imaging with Ultra-High Spatial Resolution and Chemical Sensitivity

['FUNDING_SBIR_1'] · ACTOPROBE, LLC · NIH-10922631

This study is working on a new type of microscope that can see tiny details and identify single molecules linked to infectious diseases, which could help doctors find and treat infections faster and more accurately than current methods.

Quick facts

Phase['FUNDING_SBIR_1']
Study typeNih_funding
SexAll
SponsorACTOPROBE, LLC (nih funded)
Locations1 site (ALBUQUERQUE, UNITED STATES)
Trial IDNIH-10922631 on ClinicalTrials.gov

What this research studies

This research focuses on creating a novel optical scanning probe microscope that can achieve ultra-high spatial resolution and chemical sensitivity. By utilizing advanced techniques like scanning near-field optical microscopy and tip-enhanced Raman spectroscopy, the project aims to visualize and identify single molecules related to infectious diseases. This could significantly improve the detection of pathogens, which is crucial for timely diagnosis and treatment. The approach seeks to overcome the limitations of traditional methods that often rely on growing cultures or specific antibodies.

Who could benefit from this research

Good fit: Ideal candidates for this research would include individuals with infections caused by difficult-to-detect pathogens, particularly in low- and middle-income countries.

Not a fit: Patients with well-characterized infections that can be easily diagnosed using existing methods may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to faster and more accurate identification of infectious agents, improving patient outcomes.

How similar studies have performed: While the approach is innovative, similar technologies have shown promise in other contexts, suggesting potential for success in this novel application.

Where this research is happening

ALBUQUERQUE, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.