Developing a new method to replace damaged facet joint cartilage
Toward tissue engineering of facet cartilage
['FUNDING_R01'] · UNIVERSITY OF CALIFORNIA-IRVINE · NIH-11037980
This study is working on a new implant for the small joints in your spine to help improve movement and reduce the need for major surgery, and it’s being tested in minipigs to make sure it works well with the body.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA-IRVINE (nih funded) |
| Locations | 1 site (IRVINE, UNITED STATES) |
| Trial ID | NIH-11037980 on ClinicalTrials.gov |
What this research studies
This research focuses on creating a new type of implant for facet joints, which are crucial for spinal movement. The project aims to engineer a cartilage replacement that mimics the natural properties of healthy tissue, using advanced techniques like 3D printing and specific biochemical treatments. The implant will be tested in minipigs to ensure it integrates well with the surrounding bone and functions effectively. This approach could lead to less invasive surgical methods for patients needing joint replacements.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals suffering from facet joint degeneration or injury, particularly those who may require surgical intervention.
Not a fit: Patients with conditions unrelated to facet joint issues or those who are not candidates for joint replacement surgery may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide patients with a more effective and durable solution for facet joint damage, potentially improving mobility and reducing pain.
How similar studies have performed: Previous research in tissue engineering and joint replacement has shown promising results, indicating that this approach could lead to significant advancements in treatment.
Where this research is happening
IRVINE, UNITED STATES
- UNIVERSITY OF CALIFORNIA-IRVINE — IRVINE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ATHANASIOU, KYRIACOS A — UNIVERSITY OF CALIFORNIA-IRVINE
- Study coordinator: ATHANASIOU, KYRIACOS A
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.