Developing a new method to prevent pregnancy and HIV in adolescents assigned female at birth

RP5 MPT Study

NIH-funded research Florida State University · NIH-10993609

This study is looking to help young people assigned female at birth in the U.S. by creating a new way to prevent unplanned pregnancies and HIV, using a long-lasting shot that combines birth control and an HIV prevention drug, so they can have more options for staying healthy and safe.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionFlorida State University NIH-funded
Lab location1 site (Tallahassee, United States)
Project IDNIH-10993609 on NIH RePORTER

What this research studies

This research focuses on addressing the unmet sexual and reproductive health needs of adolescents assigned female at birth (AFAB) in the U.S., particularly regarding unplanned pregnancies and HIV prevention. It aims to develop a multi-purpose prevention technology (MPT) that combines an injectable contraceptive with an HIV prevention drug, cabotegravir (CAB). The study will explore the preferences of AFAB adolescents for discreet and long-lasting prevention methods, utilizing a novel drug delivery system that could provide protection for at least three months. By engaging with this population, the research seeks to improve health outcomes and increase the uptake of preventive measures among youth.

Who could benefit from this research

Good fit: Ideal candidates for this research are adolescents assigned female at birth, particularly those who are at risk for unplanned pregnancies or HIV.

Not a fit: Patients who are not assigned female at birth or those who are not at risk for pregnancy or HIV may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide a safe and effective method for preventing both unplanned pregnancies and HIV among adolescents assigned female at birth.

How similar studies have performed: Early studies have shown promise for similar approaches, particularly with the use of long-acting agents like cabotegravir for HIV prevention.

Where this research is happening

Tallahassee, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency SyndromeAcquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency SyndromeAcquired Immunodeficiency Syndrome Virus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.