Developing a new method to measure muscle health in neuromuscular diseases
3D Shearwave Elasticity Biomarker Development for Neuromuscular Disease
This study is testing a new 3D imaging method to check muscle health in people with neuromuscular disorders like Duchenne's Muscular Dystrophy and Pompe disease, aiming to provide more accurate and easier measurements to help doctors track how well treatments are working.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Duke University NIH-funded |
| Lab location | 1 site (Durham, United States) |
| Project ID | NIH-11005696 on NIH RePORTER |
What this research studies
This research focuses on creating a 3D imaging technique to assess muscle health in patients with neuromuscular disorders like Duchenne's Muscular Dystrophy and Pompe disease. Current methods for evaluating muscle function are often subjective and can lead to inaccurate assessments. The new approach uses ultrasonic shear wave elasticity imaging to provide a more precise, non-invasive measurement of muscle properties, which could help monitor disease progression and treatment responses. By improving the accuracy of muscle health assessments, this research aims to enhance patient care and treatment outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with neuromuscular disorders such as Duchenne's Muscular Dystrophy or Pompe disease.
Not a fit: Patients with neuromuscular disorders who are not undergoing treatment or those with conditions unrelated to muscle health may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a reliable and non-invasive way to monitor muscle health, leading to better treatment decisions for patients with neuromuscular diseases.
How similar studies have performed: Other research has shown promise in using similar imaging techniques for assessing muscle health, indicating that this approach could be a significant advancement in the field.
Where this research is happening
Durham, United States
- Duke University — Durham, United States (Active)
Researchers
- Principal investigator: Nightingale, Kathryn Radabaugh — Duke University
- Study coordinator: Nightingale, Kathryn Radabaugh
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.