Developing a new method to map proteins in brain tissues
A scalable mass spectrometry platform for proteome mapping of brain tissues
['FUNDING_OTHER'] · BATTELLE PACIFIC NORTHWEST LABORATORIES · NIH-10370198
This study is working on a new way to look closely at proteins in brain cells, which could help us understand how different types of brain cells work together, and this might lead to better treatments for brain-related conditions.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | BATTELLE PACIFIC NORTHWEST LABORATORIES (nih funded) |
| Locations | 1 site (RICHLAND, UNITED STATES) |
| Trial ID | NIH-10370198 on ClinicalTrials.gov |
What this research studies
This research focuses on creating a scalable mass spectrometry platform to analyze proteins in brain tissues at a single-cell level. By improving sample preparation and detection sensitivity, the researchers aim to provide a detailed 3D characterization of brain cells, which is crucial for understanding the complexity of the brain. This innovative approach will help bridge the gap between protein and mRNA analysis, offering insights into how different brain cells are organized and function. Patients may benefit from advancements in brain-related disorders through a better understanding of brain cell heterogeneity.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals with neurological disorders or conditions affecting brain function.
Not a fit: Patients with conditions unrelated to brain function or those who do not have access to the research location may not receive benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to breakthroughs in understanding brain disorders and developing targeted treatments.
How similar studies have performed: Other research has shown success in using advanced proteomics technologies for tissue analysis, indicating a promising potential for this novel approach.
Where this research is happening
RICHLAND, UNITED STATES
- BATTELLE PACIFIC NORTHWEST LABORATORIES — RICHLAND, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SHI, TUJIN — BATTELLE PACIFIC NORTHWEST LABORATORIES
- Study coordinator: SHI, TUJIN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.