Developing a new method to create complex nitrogen-containing compounds for medicine
Official title: Ti-catalyzed cascading hydroaminoalkylation as a route to complex functionalized amines
Funded at University of Minnesota · NIH-10931373 · Data updated 2026-11-12
This study is exploring a new way to make important building blocks for medicines using a simple one-step process, which could help create new drugs that might benefit patients in the future.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Minnesota NIH-funded |
| Lab location | 1 site (Minneapolis, United States) |
| Project start | August 18, 2023 |
| Project end | August 17, 2025 |
| Funding year | 2024 |
| Award (this year) | $73,828 |
| NIH project number | 5F32GM151788-02 |
| Project ID | NIH-10931373 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research would be individuals with conditions that could be treated by new nitrogen-containing pharmaceutical agents.
✕Less likely to help
Patients who are not affected by conditions treatable with nitrogen-containing drugs may not receive any benefit from this research.
What this research studies
This research focuses on creating a novel titanium-catalyzed reaction that allows for the efficient synthesis of complex nitrogen-containing molecules, which are important in pharmaceuticals. By using a one-step process, the researchers aim to produce β-cycloalkyl amines from readily available starting materials. This innovative approach could lead to the development of new drugs and enhance our understanding of chemical reactions that build molecular complexity. Patients may benefit from new medications derived from these compounds in the future.
Why it matters
Potential benefit: If successful, this research could lead to the development of new and more effective medications for various health conditions.
How similar studies have gone: Other research in organic chemistry and catalysis has shown success in developing new synthetic methods, indicating potential for this approach to yield valuable results.
Where this research is happening
-
University of Minnesota
Minneapolis, United States Active
Researchers
- Principal investigator: Vang, Zoua PA — University of Minnesota
- Study coordinator: Vang, Zoua PA
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.