Developing a new method to create complex nitrogen-containing compounds for medicine
Ti-catalyzed cascading hydroaminoalkylation as a route to complex functionalized amines
['FUNDING_FELLOWSHIP'] · UNIVERSITY OF MINNESOTA · NIH-10931373
This study is exploring a new way to make important building blocks for medicines using a simple one-step process, which could help create new drugs that might benefit patients in the future.
Quick facts
| Phase | ['FUNDING_FELLOWSHIP'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF MINNESOTA (nih funded) |
| Locations | 1 site (MINNEAPOLIS, UNITED STATES) |
| Trial ID | NIH-10931373 on ClinicalTrials.gov |
What this research studies
This research focuses on creating a novel titanium-catalyzed reaction that allows for the efficient synthesis of complex nitrogen-containing molecules, which are important in pharmaceuticals. By using a one-step process, the researchers aim to produce β-cycloalkyl amines from readily available starting materials. This innovative approach could lead to the development of new drugs and enhance our understanding of chemical reactions that build molecular complexity. Patients may benefit from new medications derived from these compounds in the future.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research would be individuals with conditions that could be treated by new nitrogen-containing pharmaceutical agents.
Not a fit: Patients who are not affected by conditions treatable with nitrogen-containing drugs may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of new and more effective medications for various health conditions.
How similar studies have performed: Other research in organic chemistry and catalysis has shown success in developing new synthetic methods, indicating potential for this approach to yield valuable results.
Where this research is happening
MINNEAPOLIS, UNITED STATES
- UNIVERSITY OF MINNESOTA — MINNEAPOLIS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: VANG, ZOUA PA — UNIVERSITY OF MINNESOTA
- Study coordinator: VANG, ZOUA PA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.