Developing a new method to create a unique natural compound from deep ocean sponges

Synthesis and Optimization of the Aleutianamine Class of Alkaloids

['FUNDING_R01'] · MEDICAL UNIVERSITY OF SOUTH CAROLINA · NIH-11100349

This study is exploring a special substance called aleutianamine, which comes from a sponge in the Aleutian Islands, to see if it can help create new medicines for different diseases that could benefit patients like you.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorMEDICAL UNIVERSITY OF SOUTH CAROLINA (nih funded)
Locations1 site (CHARLESTON, UNITED STATES)
Trial IDNIH-11100349 on ClinicalTrials.gov

What this research studies

This research focuses on creating a reliable synthesis method for aleutianamine, a unique alkaloid derived from a sponge found in the Aleutian Islands. By investigating the chemical properties and potential therapeutic applications of this compound, the research aims to enhance our understanding of its mechanisms and pharmacology. The approach involves extensive laboratory work to replicate the natural production of aleutianamine, which could lead to new treatments for various diseases. Patients may benefit from the eventual development of medications derived from this compound.

Who could benefit from this research

Good fit: Ideal candidates for participation or benefit from this research would be individuals suffering from diseases that could be treated with new medications derived from aleutianamine.

Not a fit: Patients with conditions unrelated to the therapeutic applications of aleutianamine may not receive any benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new therapeutic options for diseases that currently lack effective treatments.

How similar studies have performed: While the specific synthesis of aleutianamine is novel, similar approaches in developing natural products have shown promise in other research.

Where this research is happening

CHARLESTON, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.