Developing a new method to analyze sugars in biological samples using DNA coding and sequencing.
Next Generation Glycan Microarray using DNA-coded glycans and Next Generation Sequencing (NGS)
This study is working on a new way to easily and affordably analyze how sugars interact with proteins, which could help improve tests and treatments for health issues related to these interactions, making it beneficial for patients.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project ID | NIH-10671639 on NIH RePORTER |
What this research studies
This research focuses on creating an advanced glycan microarray that utilizes DNA sequences to represent different sugars, allowing for more accessible and cost-effective analysis of protein-sugar interactions. By employing Next Generation Sequencing (NGS), the project aims to simplify the process of studying glycans, which are crucial for understanding various biological functions and diseases. Patients may benefit from this research as it could lead to improved diagnostic tools and treatments for conditions related to glycan interactions.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions related to glycan interactions, such as certain autoimmune diseases or infections.
Not a fit: Patients who do not have conditions associated with glycan interactions may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could enhance the understanding and treatment of diseases linked to glycan interactions, potentially leading to better diagnostic and therapeutic options for patients.
How similar studies have performed: Previous research in glycan microarray technology has shown significant success, indicating that this approach has the potential to advance the field further.
Where this research is happening
Atlanta, United States
- Emory University — Atlanta, United States (Active)
Researchers
- Principal investigator: Song, Xuezheng — Emory University
- Study coordinator: Song, Xuezheng
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.