Developing a new method for quickly detecting filoviruses like Ebola and Marburg.
PANDAA for universal, pan-lineage molecular detection of filoviruses to enable rapid epidemic response.
This study is working on a new way to quickly and accurately detect Ebola and Marburg viruses, which cause serious illnesses, so that we can better manage outbreaks and keep people safe.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Aldatu Biosciences, INC. NIH-funded |
| Lab location | 1 site (Watertown, UNITED STATES) |
| Project ID | NIH-10899546 on NIH RePORTER |
What this research studies
This research focuses on improving the detection of filoviruses, specifically Ebolavirus and Marburgvirus, which cause severe hemorrhagic fevers. The current diagnostic methods struggle due to the genetic variability of these viruses, making early detection challenging. The study utilizes a novel technology called PANDAA, which enhances the accuracy of qPCR tests by adapting to diverse viral genetic sequences. This approach aims to provide rapid and reliable diagnostics to help control outbreaks effectively.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals in regions where filovirus outbreaks occur, particularly those showing symptoms consistent with hemorrhagic fevers.
Not a fit: Patients who are not in outbreak areas or do not exhibit symptoms related to filovirus infections may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to faster and more accurate detection of filoviruses, improving outbreak response and patient outcomes.
How similar studies have performed: Previous research has shown promise in developing rapid diagnostic methods for other infectious diseases, suggesting potential success for this novel approach.
Where this research is happening
Watertown, UNITED STATES
- Aldatu Biosciences, INC. — Watertown, United States (Active)
Researchers
- Principal investigator: Macleod, Iain James — Aldatu Biosciences, INC.
- Study coordinator: Macleod, Iain James
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.