Developing a new method for faster and more accurate DNA sequencing
Super-resolution single-molecule sequencing by observing the dynamic hybridization of a repertoire of oligonucleotides to DNA targets
['FUNDING_SBIR_1'] · XGENOMES CORP. · NIH-11008187
This study is working on a new way to read DNA that could make it easier and cheaper to track conditions like cancer and genetic disorders, using special imaging techniques to get more accurate results.
Quick facts
| Phase | ['FUNDING_SBIR_1'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | XGENOMES CORP. (nih funded) |
| Locations | 1 site (CAMBRIDGE, UNITED STATES) |
| Trial ID | NIH-11008187 on ClinicalTrials.gov |
What this research studies
This research focuses on creating an innovative DNA sequencing platform that improves upon current technologies. By using super-resolution fluorescence imaging, the method reads short segments of DNA sequences more efficiently, allowing for multiple readings of each nucleotide. Advanced algorithms will process the images and assemble the sequences, aiming to significantly enhance accuracy and reduce costs. This could lead to better monitoring of conditions like cancer and genetic disorders.
Who could benefit from this research
Good fit: Ideal candidates include individuals undergoing genetic testing for conditions such as cancer or cystic fibrosis.
Not a fit: Patients who do not require genetic testing or monitoring for genetic conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide patients with more accurate and cost-effective DNA sequencing, improving disease monitoring and treatment options.
How similar studies have performed: Previous research has shown promise in using super-resolution imaging for DNA sequencing, indicating potential success for this novel approach.
Where this research is happening
CAMBRIDGE, UNITED STATES
- XGENOMES CORP. — CAMBRIDGE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MIR, KALIM ULLAH — XGENOMES CORP.
- Study coordinator: MIR, KALIM ULLAH
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cancers