Developing a new method for accurate protein sequencing using nanopores

Controlled Protein Translocation in Nanopores for Sequencing Applications

['FUNDING_R21'] · ELECTRONIC BIOSCIENCES, INC. · NIH-10878689

This study is working on a new way to read proteins really well, which could help us learn more about how proteins work and their connection to diseases, ultimately benefiting patients like you.

Quick facts

Phase['FUNDING_R21']
Study typeNih_funding
SexAll
SponsorELECTRONIC BIOSCIENCES, INC. (nih funded)
Locations1 site (SAN DIEGO, UNITED STATES)
Trial IDNIH-10878689 on ClinicalTrials.gov

What this research studies

This research focuses on creating a novel technology for sequencing proteins with high accuracy and sensitivity. By using nanopores, the team aims to control the translocation of proteins through a tiny opening, allowing for detailed analysis of individual protein molecules. The project will involve building a prototype system and optimizing the methods to ensure effective sequencing of both abundant and rare proteins. Patients may benefit from advancements in understanding protein functions and their roles in diseases.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals with conditions related to protein misfolding or abnormalities, such as certain genetic disorders or cancers.

Not a fit: Patients with conditions unrelated to protein function or those who do not require protein analysis may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more accurate and cost-effective protein sequencing, enhancing disease diagnosis and treatment.

How similar studies have performed: Other research has shown promise in nanopore sequencing technologies, indicating potential for success in this novel approach.

Where this research is happening

SAN DIEGO, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.