Developing a new method for accurate protein sequencing using nanopores
Official title: Controlled Protein Translocation in Nanopores for Sequencing Applications
Funded at Electronic Biosciences, INC. · NIH-10878689 · Data updated 2026-11-12
This study is working on a new way to read proteins really well, which could help us learn more about how proteins work and their connection to diseases, ultimately benefiting patients like you.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Electronic Biosciences, INC. NIH-funded |
| Lab location | 1 site (San Diego, United States) |
| Project start | July 1, 2023 |
| Project end | June 30, 2025 |
| Funding year | 2024 |
| Award (this year) | $219,055 |
| NIH project number | 5R21GM148844-02 |
| Project ID | NIH-10878689 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with conditions related to protein misfolding or abnormalities, such as certain genetic disorders or cancers.
✕Less likely to help
Patients with conditions unrelated to protein function or those who do not require protein analysis may not benefit from this research.
What this research studies
This research focuses on creating a novel technology for sequencing proteins with high accuracy and sensitivity. By using nanopores, the team aims to control the translocation of proteins through a tiny opening, allowing for detailed analysis of individual protein molecules. The project will involve building a prototype system and optimizing the methods to ensure effective sequencing of both abundant and rare proteins. Patients may benefit from advancements in understanding protein functions and their roles in diseases.
Why it matters
Potential benefit: If successful, this research could lead to more accurate and cost-effective protein sequencing, enhancing disease diagnosis and treatment.
How similar studies have gone: Other research has shown promise in nanopore sequencing technologies, indicating potential for success in this novel approach.
Where this research is happening
-
Electronic Biosciences, INC.
San Diego, United States Active
Researchers
- Principal investigator: Peterson, Eric Mayo — Electronic Biosciences, INC.
- Study coordinator: Peterson, Eric Mayo
Related research
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Developing advanced RNA sequencing technologies to understand gene expression and modifications.
This study is working on new ways to read RNA directly, which helps us see how genes work and how changes in RNA can affect our cells, making it easier to understand diseases and improve treatments.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.