Developing a new liposome-based adjuvant for COVID-19 vaccines
ADVANCED DEVELOPMENT OF LQ A LIPOSOME-BASED SAPONIN-CONTAINING ADJUVANT FOR USE IN PANSARBECOVIRUS VACCINES
This study is working on a new ingredient to boost the effectiveness of COVID-19 vaccines, making them stronger and more affordable, so that more people can benefit from better protection against the virus.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Vaccine Formulation Institute (Ch) LTD NIH-funded |
| Lab location | 1 site (Plan-Les-Ouates, Switzerland) |
| Project ID | NIH-11126499 on NIH RePORTER |
What this research studies
This research focuses on creating a novel vaccine adjuvant that enhances immune responses specifically for COVID-19 vaccines. It involves formulating a cost-effective saponin fraction within a liposome carrier to improve the vaccine's effectiveness. The project includes optimizing the formulation and conducting extensive preclinical studies to evaluate the adjuvant's safety and immunogenicity. Ultimately, the goal is to make this adjuvant widely available to the vaccine development community.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who are at risk of COVID-19 and may benefit from enhanced vaccine responses.
Not a fit: Patients who are not at risk for COVID-19 or those who have already received effective vaccinations may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and affordable COVID-19 vaccines.
How similar studies have performed: Other research has shown promise in using liposome-based adjuvants for vaccine development, indicating a potential for success in this approach.
Where this research is happening
Plan-Les-Ouates, Switzerland
- Vaccine Formulation Institute (Ch) LTD — Plan-Les-Ouates, Switzerland (Active)
Researchers
- Principal investigator: Collins, Nicolas — Vaccine Formulation Institute (Ch) LTD
- Study coordinator: Collins, Nicolas
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.