Developing a new lens for recording brain activity

A multi-foci objective lens for large scale brain activity recording

['FUNDING_R21'] · CORNELL UNIVERSITY · NIH-10906220

This study is working on a new type of special lens that helps scientists see brain activity more clearly and quickly, which could help us learn more about how the brain works in living creatures.

Quick facts

Phase['FUNDING_R21']
Study typeNih_funding
SexAll
SponsorCORNELL UNIVERSITY (nih funded)
Locations1 site (ITHACA, UNITED STATES)
Trial IDNIH-10906220 on ClinicalTrials.gov

What this research studies

This research focuses on creating an innovative bifocal lens that can simultaneously capture brain activity at different depths using two-photon and three-photon microscopy techniques. By allowing for faster imaging of large brain regions, this approach aims to enhance our understanding of neural circuits in living organisms. The lens will be designed to maintain high spatial resolution while enabling the collection of data from both shallow and deep brain tissues. This could lead to significant advancements in brain imaging technology.

Who could benefit from this research

Good fit: Ideal candidates for this research would include individuals with neurological conditions or those participating in studies related to brain function and imaging.

Not a fit: Patients with conditions unrelated to brain activity or those who do not require advanced imaging techniques may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could greatly improve the ability to study brain function and disorders by providing clearer and more comprehensive images of neural activity.

How similar studies have performed: While the approach of combining two-photon and three-photon microscopy is innovative, similar imaging techniques have shown promise in other studies, indicating potential for success.

Where this research is happening

ITHACA, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Cancer Biology

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.