Developing a new imaging tool to measure tissue oxygen and pH levels
Official title: Multifunctional EPRI Instrument to Advance Therapies in Biomedical Sciences
Funded at O2m Technologies, LLC · NIH-10919608 · Data updated 2026-11-12
This study is working on a new imaging device that can check oxygen levels and acidity in tissues at the same time, which could help doctors and researchers better understand different health conditions and find better treatments.
Quick facts
| Grant type | Sbir 1 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | O2m Technologies, LLC NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project start | September 3, 2024 |
| Project end | August 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $400,000 |
| NIH project number | 1R43CA285033-01A1 |
| Project ID | NIH-10919608 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research would include patients with conditions that affect tissue oxygenation and acidity, such as cancers and brittle diabetes.
✕Less likely to help
Patients with conditions unrelated to tissue oxygen or pH levels may not benefit from this research.
What this research studies
This research focuses on creating a multifunctional imaging device that can simultaneously measure important parameters in tissues, specifically oxygen levels and acidity (pH). By utilizing advanced electron paramagnetic resonance imaging (EPRI) techniques, the project aims to develop an instrument that combines different imaging methods to provide comprehensive maps of tissue microenvironments. This could help researchers better understand various medical conditions and improve treatment strategies. The project involves designing new hardware and electronics to support these imaging capabilities.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic tools that enhance the understanding and treatment of various diseases, including cancers and diabetes.
How similar studies have gone: Previous research has shown promise in using EPRI techniques for imaging, but this specific multifunctional approach is novel and has not been extensively tested.
Where this research is happening
-
O2m Technologies, LLC
Chicago, United States Active
Researchers
- Principal investigator: Kotecha, Mrignayani — O2m Technologies, LLC
- Study coordinator: Kotecha, Mrignayani
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.