Developing a new imaging tool for biological samples
BEAMMAP: ULTRA-HIGH RESOLUTION TOPOLOGICAL AND CHEMICAL IMAGING WITH SYNERG
['FUNDING_R01'] · GEORGIA INSTITUTE OF TECHNOLOGY · NIH-10581771
This study is working on a new tool called BeamMap that helps scientists take super-detailed pictures of tiny parts of cells, which can help us learn more about important substances like proteins and fats in our bodies.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | GEORGIA INSTITUTE OF TECHNOLOGY (nih funded) |
| Locations | 1 site (ATLANTA, UNITED STATES) |
| Trial ID | NIH-10581771 on ClinicalTrials.gov |
What this research studies
This research focuses on creating an innovative instrument called BeamMap that combines Scanning Electron Microscopy with a new imaging technique known as Desorption Electrospray Ionization (DESI). The goal is to achieve ultra-high resolution imaging of biological samples at the sub-cellular level, allowing for detailed analysis of proteins, metabolites, and lipids. By improving the resolution of chemical imaging to approximately 250 nm and topological imaging to about 50 nm, this project aims to enhance our understanding of biological processes. The research involves designing and optimizing the instrument, simulating its components, and validating its performance through controlled experiments.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions that require detailed biological analysis, such as cancer or metabolic disorders.
Not a fit: Patients with conditions that do not involve cellular or molecular analysis may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly advance the field of biomedical sciences by providing new insights into cellular and molecular processes.
How similar studies have performed: Other research has shown promising results with similar imaging techniques, indicating potential for success in this novel approach.
Where this research is happening
ATLANTA, UNITED STATES
- GEORGIA INSTITUTE OF TECHNOLOGY — ATLANTA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: FEDOROV, ANDREI G — GEORGIA INSTITUTE OF TECHNOLOGY
- Study coordinator: FEDOROV, ANDREI G
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.