Developing a new imaging tool for biological samples
BeamMap: Ultra-High Resolution Topological and Chemical Imaging with Synergistic Liquid and Electron Beams
This study is working on a new tool called BeamMap that helps scientists take super detailed pictures of tiny parts of cells, which can help us learn more about important substances like proteins and fats in our bodies.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Georgia Institute of Technology NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project ID | NIH-10439918 on NIH RePORTER |
What this research studies
This research focuses on creating an innovative instrument called BeamMap that combines Scanning Electron Microscopy with a new imaging technique known as Desorption Electrospray Ionization. The goal is to achieve ultra-high resolution imaging of biological samples at the sub-cellular level, allowing for detailed analysis of proteins, metabolites, and lipids. By improving the resolution of chemical imaging to approximately 250 nm and topological imaging to about 50 nm, this project aims to enhance our understanding of biological processes. The research involves designing, optimizing, and validating this new imaging technology through advanced fabrication techniques and controlled experiments.
Who could benefit from this research
Good fit: Ideal candidates for benefiting from this research include individuals with conditions that require detailed biological analysis, such as cancer or metabolic disorders.
Not a fit: Patients with conditions that do not involve cellular or molecular analysis may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could significantly advance the field of biomedical sciences by providing unprecedented insights into cellular structures and functions.
How similar studies have performed: While the approach of combining these imaging techniques is innovative, similar imaging advancements have shown promise in enhancing biological research.
Where this research is happening
Atlanta, United States
- Georgia Institute of Technology — Atlanta, United States (Active)
Researchers
- Principal investigator: Fedorov, Andrei G — Georgia Institute of Technology
- Study coordinator: Fedorov, Andrei G
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.