Developing a new imaging technique for breast cancer detection
Official title: A Single-Sided Magnetic Particle Imaging Scanner for In Vivo Breast Cancer Imaging
Funded at Oakland University · NIH-10874920 · Data updated 2026-11-12
This study is testing a new type of imaging machine that can take clear pictures of breast cancer without using harmful radiation, making it safer for both people and small animals.
Quick facts
| Grant type | R15 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Oakland University NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project start | September 3, 2019 |
| Project end | May 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $461,895 |
| NIH project number | 2R15EB028535-03 |
| Project ID | NIH-10874920 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with breast cancer who require advanced imaging techniques for better diagnosis and treatment planning.
✕Less likely to help
Patients who do not have breast cancer or those who are not eligible for imaging studies may not benefit from this research.
What this research studies
This research focuses on creating a specialized Magnetic Particle Imager (MPI) that can provide non-invasive imaging for breast cancer without using harmful radiation or toxic substances. The innovative design features a single-sided scanner that can be used for both small animals and humans, allowing for detailed imaging of cancerous tissues. By utilizing a unique field-free line geometry, this approach aims to enhance image quality and resolution significantly. The ultimate goal is to demonstrate the effectiveness of this technology in imaging breast cancer in live subjects.
Why it matters
Potential benefit: If successful, this research could lead to safer and more effective imaging techniques for breast cancer diagnosis.
How similar studies have gone: While Magnetic Particle Imaging is a relatively novel approach, preliminary studies have shown promise in similar imaging techniques, indicating potential for success.
Where this research is happening
-
Oakland University
Rochester, United States Active
Researchers
- Principal investigator: Tonyushkin, Alexey a — Oakland University
- Study coordinator: Tonyushkin, Alexey a
Related research
Other NIH-funded projects on the same topics.
-
Improving Breast Cancer Guideline Adherence in Nigeria
Aimed at helping doctors in Nigeria follow international guideline-based breast cancer care to improve outcomes for women with breast cancer.
-
Genomic study to understand how genetics and epigenetics shape triple-negative breast cancer in African ancestry
This study looks at how inherited genes and gene activity affect triple-negative breast cancer in people of African ancestry to better understand why outcomes can be worse.
-
Translational breast cancer research to improve treatment options
A comprehensive program at Baylor College of Medicine is focusing on breast cancer; researchers will advance targeted therapies and biomarkers to help patients with aggressive or hard-to-treat forms.
-
Cancer Pain Management for Asian American Breast Cancer Survivors with Depressive Symptoms
A technology-based program helps Asian American breast cancer survivors with depressive symptoms manage chronic pain more effectively from home using a web app and mobile tools.
-
Co-Targeting IL-6 and CDK4/6 to Prevent TNBC in Women Veterans
A study aims to block two cancer-promoting pathways (IL-6 and CDK4/6) to prevent or reduce progression of triple-negative breast cancer in women veterans.
-
Gut bacteria and metabolites linked to breast density and cancer risk
A small, patient-friendly study will explore whether gut bacteria and their byproducts are connected to high breast density, which can raise cancer risk and make screening less accurate.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.