Developing a new HIV vaccine using liposomes and mRNA technology
Official title: Feasibility for Development of a Liposome/LNP Displaying an HIV Env Trimer Protein and Containing/Incorporating an mRNA
Funded at Advanced Bioscience Laboratories, INC. · NIH-11181790 · Data updated 2026-11-12
This study is working on a new HIV vaccine that uses tiny bubbles to deliver important proteins and messages to help your body fight the virus, with the hope of making vaccines more effective for everyone.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Advanced Bioscience Laboratories, INC. NIH-funded |
| Lab location | 1 site (Kensington, United States) |
| Project start | August 31, 2024 |
| Project end | August 27, 2028 |
| Funding year | 2024 |
| Award (this year) | $1,863,405 |
| NIH project number | 75N93022D00004-0-759302400001-1 |
| Project ID | NIH-11181790 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals at risk of HIV infection or those living with HIV who are seeking new treatment options.
✕Less likely to help
Patients who are not at risk for HIV or those who are already receiving effective treatment may not benefit from this research.
What this research studies
This research focuses on creating a novel vaccine for HIV by using liposomes that display an HIV envelope protein and incorporate mRNA. The approach involves preclinical and translational development, which includes small-scale production and testing of the vaccine. Patients may benefit from this research as it aims to improve the effectiveness of HIV vaccines, potentially leading to better prevention strategies against the virus. The study will also assess the feasibility of this innovative vaccine development process.
Why it matters
Potential benefit: If successful, this research could lead to a more effective HIV vaccine, enhancing prevention efforts and improving public health outcomes.
How similar studies have gone: Other research has shown promise in using similar liposomal and mRNA technologies for vaccine development, indicating potential for success in this area.
Where this research is happening
-
Advanced Bioscience Laboratories, INC.
Kensington, United States Active
Researchers
- Principal investigator: Fouts, Timothy R — Advanced Bioscience Laboratories, INC.
- Study coordinator: Fouts, Timothy R
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.