Developing a new HIV vaccine using liposomes and mRNA technology
Feasibility for Development of a Liposome/LNP Displaying an HIV Env Trimer Protein and Containing/Incorporating an mRNA
['FUNDING_OTHER'] · ADVANCED BIOSCIENCE LABORATORIES, INC. · NIH-11181790
This study is working on a new HIV vaccine that uses tiny bubbles to deliver important proteins and messages to help your body fight the virus, with the hope of making vaccines more effective for everyone.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | ADVANCED BIOSCIENCE LABORATORIES, INC. (nih funded) |
| Locations | 1 site (KENSINGTON, UNITED STATES) |
| Trial ID | NIH-11181790 on ClinicalTrials.gov |
What this research studies
This research focuses on creating a novel vaccine for HIV by using liposomes that display an HIV envelope protein and incorporate mRNA. The approach involves preclinical and translational development, which includes small-scale production and testing of the vaccine. Patients may benefit from this research as it aims to improve the effectiveness of HIV vaccines, potentially leading to better prevention strategies against the virus. The study will also assess the feasibility of this innovative vaccine development process.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals at risk of HIV infection or those living with HIV who are seeking new treatment options.
Not a fit: Patients who are not at risk for HIV or those who are already receiving effective treatment may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to a more effective HIV vaccine, enhancing prevention efforts and improving public health outcomes.
How similar studies have performed: Other research has shown promise in using similar liposomal and mRNA technologies for vaccine development, indicating potential for success in this area.
Where this research is happening
KENSINGTON, UNITED STATES
- ADVANCED BIOSCIENCE LABORATORIES, INC. — KENSINGTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: FOUTS, TIMOTHY R — ADVANCED BIOSCIENCE LABORATORIES, INC.
- Study coordinator: FOUTS, TIMOTHY R
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Acquired Immune Deficiency Syndrome Virus, Acquired Immunodeficiency Syndrome Virus