Developing a new eye drop to lower eye pressure for glaucoma patients

Late-stage Pre-clinical Development and GMP Production of a First-in-Class Extended Release IOP-lowering Formulation

['FUNDING_SBIR_2'] · TAVO BIOTHERAPEUTICS, INC · NIH-10922072

This study is working on a new type of eye drop that lasts longer and helps lower eye pressure for people with glaucoma, making it easier for them to stick to their treatment and experience fewer side effects.

Quick facts

Phase['FUNDING_SBIR_2']
Study typeNih_funding
SexAll
SponsorTAVO BIOTHERAPEUTICS, INC (nih funded)
Locations1 site (MEMPHIS, UNITED STATES)
Trial IDNIH-10922072 on ClinicalTrials.gov

What this research studies

This research focuses on creating a first-in-class extended release formulation of eye drops designed to lower intraocular pressure (IOP) in patients with glaucoma. The approach aims to improve patient adherence by reducing the frequency of eye drop administration and minimizing side effects associated with current treatments. By engineering a more effective delivery system, the research seeks to provide a sustained IOP-lowering effect, addressing the critical need for better management of this condition. The study will involve pre-clinical development and adherence to Good Manufacturing Practices (GMP) to ensure safety and efficacy.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults diagnosed with glaucoma who struggle with current treatment regimens due to side effects or adherence issues.

Not a fit: Patients who do not have glaucoma or those who are not able to use eye drops may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to a more effective and convenient treatment option for glaucoma patients, potentially reducing the risk of blindness.

How similar studies have performed: Previous research has shown promise in developing extended release formulations for other conditions, suggesting potential success for this novel approach in glaucoma treatment.

Where this research is happening

MEMPHIS, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.