Developing a new device to study brain function in primates
Smart Dura: A Functional Large-scale, High-Density Optoelectric Dura for Non-Human Primates
['FUNDING_R01'] · CARNEGIE-MELLON UNIVERSITY · NIH-10900580
This study is testing a new device called 'smart dura' that helps scientists better understand how the brain works by allowing them to record and stimulate brain activity in monkeys more effectively than before.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | CARNEGIE-MELLON UNIVERSITY (nih funded) |
| Locations | 1 site (PITTSBURGH, UNITED STATES) |
| Trial ID | NIH-10900580 on ClinicalTrials.gov |
What this research studies
This research focuses on creating a novel optoelectric interface called 'smart dura' that allows for advanced manipulation and recording of brain activity in non-human primates. By embedding thousands of electrodes and optical stimulation sites into a device that mimics the natural dura mater, researchers aim to enhance the precision and scale of neural circuit studies. This technology will enable simultaneous recordings and stimulation across a large area of the brain, providing insights into brain function and behavior. The approach is designed to overcome limitations of current methods used in primate studies, which have lagged behind those in smaller animal models.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research would include non-human primates, particularly macaques, used in neuroscience studies.
Not a fit: Patients who are not non-human primates or those not involved in neuroscience research may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly improve our understanding of brain function and lead to advancements in treatments for neurological disorders.
How similar studies have performed: While optogenetics has shown success in smaller animal models, this approach in non-human primates is novel and has not been extensively tested.
Where this research is happening
PITTSBURGH, UNITED STATES
- CARNEGIE-MELLON UNIVERSITY — PITTSBURGH, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: CHAMANZAR, MAYSAMREZA — CARNEGIE-MELLON UNIVERSITY
- Study coordinator: CHAMANZAR, MAYSAMREZA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.