Developing a new COVID-19 vaccine for older adults
Novel delivery platform and antigen design for an effective COVID-19 vaccine
This study is testing a new type of vaccine made for older adults to help boost their immune response against COVID-19, making it safer and more effective for them.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Purdue University NIH-funded |
| Lab location | 1 site (West Lafayette, United States) |
| Project ID | NIH-10669131 on NIH RePORTER |
What this research studies
This research focuses on creating a novel vaccine platform specifically designed to enhance immune responses in older adults, who are at higher risk for severe COVID-19. The approach utilizes a unique bovine adenovirus-based vaccine that aims to improve the effectiveness and safety of COVID-19 vaccination in the elderly population. By addressing the decline in immune function associated with aging, the research seeks to provide a more robust and protective vaccine option. The study will involve testing the vaccine's ability to generate strong immune responses and its overall effectiveness against the virus.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults, particularly those aged 65 and above, who are at increased risk for severe COVID-19.
Not a fit: Patients who are younger than 65 or those who do not have any underlying health conditions related to COVID-19 may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to a more effective COVID-19 vaccine tailored for older adults, potentially reducing their risk of severe illness.
How similar studies have performed: Other research has shown promise in developing vaccines using adenoviral vectors, indicating that this approach could be effective.
Where this research is happening
West Lafayette, United States
- Purdue University — West Lafayette, United States (Active)
Researchers
- Principal investigator: Mittal, Suresh K — Purdue University
- Study coordinator: Mittal, Suresh K
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.