Developing a new contraceptive method using antibodies
Antibody-based Contraceptive MPTs: Advancing the Human Contraceptive Antibody (HCA) through Clinical Trials
This study is testing a new vaginal film that uses special antibodies to help prevent pregnancy and sexually transmitted infections, and it's designed for women who want a safe and effective contraceptive option.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston University Medical Campus NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10923979 on NIH RePORTER |
What this research studies
This research focuses on creating innovative contraceptive products that utilize monoclonal antibodies to prevent unintended pregnancies and sexually transmitted infections. The team has developed a vaginal film containing these antibodies, which has shown promising safety and efficacy in early clinical trials. Currently, they are testing a new formulation in women to assess its effectiveness in preventing sperm from entering the cervix, which is crucial for contraception. The goal is to advance this product through further clinical trials to ensure its safety and effectiveness for broader use.
Who could benefit from this research
Good fit: Ideal candidates for participation are women seeking effective contraception and protection against sexually transmitted infections.
Not a fit: Patients who are not seeking contraception or who are not at risk for sexually transmitted infections may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a new, effective contraceptive method that also protects against sexually transmitted infections.
How similar studies have performed: Other research has shown success with similar antibody-based approaches in contraception and STI prevention, indicating a promising avenue for further exploration.
Where this research is happening
Boston, United States
- Boston University Medical Campus — Boston, United States (Active)
Researchers
- Principal investigator: Anderson, Deborah J — Boston University Medical Campus
- Study coordinator: Anderson, Deborah J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.